Aktivitas Antimalaria Senyawa Flavanon Terisoprenilasi Dari Kulit Batang Erythrina fusca L
نویسندگان
چکیده
منابع مشابه
Cinnamic Acid Derivate From the Bark of Lerchea bracteata Val
Penyelidikan kandungan kimia dari batang tumbuhan Lerchea brateata Val telah dilakukan dan berhasil mendapatkan senyawa asam 3,4-dihidroksisinamatmetil ester yang diisolasi dari fraksi etil asetat menggunakan metoda kromatografi. Senyawa ini dimurnikan melalui proses rekristalisasi dan berbentuk kristal kekuningan dan meleleh pada 162-163 o C. Struktur dielusidasi melalui interprestasi spektrum...
متن کاملDeterminants of systolic blood pressure in Indonesian elderly men:
Tujuan penelitian ini adalah untuk mengetahui determinan tekanan darah sistolik pada kelompok lanjut usia pria. Suatu studi dengan rancangan ‘cross sectional’ dilakukan di 4 kota besar di Indonesia dengan menggunakan metoda ‘multistage random sampling’. Jumlah responden 320 orang lanjut usia pria, yang merupakan sub-sampel dari 981 responden pada penelitian yang lebih besar. Pengumpulan data di...
متن کاملAntimalaria Drug Development & Pipeline
Artemisin traditionally cleave the peroxide bond by Fe(II) found in heme proteins, thus generating toxic oxygen radicals. Synthetic peroxides, thus are proving to be useful substitutes for artemisinin. The first-generation ozonide OZ277, known as arterolane [1], has been found to inhibit the growth of chloroquine-resistant (K1) and chloroquine sensitive (NF54) parasite strains. In 2012, the com...
متن کاملTolerability of antimalaria drugs.
Sir—The multicenter randomized trial reported by Overbosch and colleagues [1] is important for 2 reasons. First, the study shows that when taken as malaria prophylaxis, mefloquine is not well tolerated by many travelers. Of the study participants randomized to receive mefloquine, 67.1% reported 1 adverse event, and, in 6% of mefloquine users, these events were severe (defined as requiring medic...
متن کاملCYP2C8 and antimalaria drug efficacy.
Malaria is a major infectious disease. In the last 10 years it has killed more than 20 million people, mainly small children in Africa. The highly efficacious artemisinine combination therapy is being launched globally, constituting the main hope for fighting the disease. Amodiaquine is a main partner in these combinations. Amodiaquine is almost entirely metabolized by the polymorphic cytochrom...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Jurnal Pharmascience
سال: 2018
ISSN: 2460-9560,2355-5386
DOI: 10.20527/jps.v5i1.5786